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Differences in indications for IV and oral ranitidine or PPI. Will IV affect the GI tract less?
I am interested in rantidine for other H1 properties than heartburn. Same with cemitidine. Thanks.
Thanks for the gentle correction on the numbering.
I suspected it was for pts who were unable to ingest it.
The only real difference between IV and PO is for people who can't take PO, as those who are actively vomiting.
None of these seems to affect GI bleeding, but the H2 blockers seem to be a pretty good adjuvant treatment for allergic problems like hives and are occasionally used to premedicate in, as an example, IV contrast radiography where there's a risk of anaphylactoid reactions, as part of a cocktail. PPI's, of course, don't make sense in these applications.
Some people also use them to decrease gastric acidity pre-operatively as a prophylactic for reflux/aspiration.
